Wisconsin Sleep Available Services

Wisconsin Sleep offers investigators a wide variety of conventional sleep laboratory procedures and tools for the collection and analysis of physiological data from sleeping human subjects. Our facility contains sixteen comfortable and attractive recording bedrooms, each equipped with private bathroom facilities, in addition to sophisticated digital recording systems linked into a local area network incorporating a large capacity server. Technical staff are available in the lab twenty four hours a day, 5 days a week. The individual bedroom suites are monitored from a large central control room, with individual workstations for each bedroom. Also built into the laboratory complex are supporting spaces: work and lounge areas, storage rooms, wet lab space, and equipment maintenance facilities.

In-laboratory studies incorporate standard digital recordings of electrophysiological, neurological, and respiratory variables that can be configured and processed to meet the needs of individual researchers and special projects. Each bedroom can host behavioral testing of research subjects with resident desktop PCs; continuous, digitized audio/video recordings are also available from each room. Research data can be supplied to researchers in raw form as digital files or as reduced and analyzed by the laboratory staff according to well-established methods, such as the Rechtschaffen and Kales or AASM 2007 sleep scoring protocols. For specific projects, custom analytic procedures can also be implemented. In addition, state-of-the-art electroencephalographic data sets are available from the laboratory, every recording suite equipped with unique high density digital electroencephalography (hd-EEG) instrumentation. These hd-EEG devices offer sophisticated signal processing and advanced analytic tools, which greatly extend the neuroscience capability of our polysomnography systems.

Ambulatory monitoring systems capable of recording actigraphy, illuminance, and cardio-respiratory data from research subjects outside of the laboratory are available, with specific setup and analysis by the laboratory staff as required by researchers.

Polysomnography

Wisconsin Sleep uses the Alice 5 polysomnography system (Respironics, Inc., Murrysville, PA) for the collection and conventional analysis of physiological data from sleeping human subjects. Data are archived on a central server and can be supplied to researchers as native files or in EDF format. Standard clinical montages are available, such as the one in the table below.

Additional physiological variables can be added to any sleep study to meet project needs, e.g., endo-esophageal pressure, end tidal CO2 concentration, transcutaneous PaCO2, pulse transit time, and other custom measurements. Contact the laboratory for details.

Standard Polysomnogram
Derivation Variable
LEOG EOG
REOG EOG
F3A2 EEG
F4A1 EEG
C3A2 EEG
C4A1 EEG
O1A2 EEG
O2A1 EEG
CHIN EMG
Rtibial Leg EMG
Ltibial Leg EMG
ECG I ECG
ECG II ECG
PulseR Pulse Rate
INT EMG EMG
SNORE Snore Mic
TFLOW Flow
PFLOW Flow
CFLOW Flow
IPAP IPAP
EPAP EPAP
LEAK Numerical
CHEST Resp Effort
ABDO Resp Effort
SpO2 SpO2
PLETH Pleth
POSITION Body Position

High Density Electroencephalography

In addition to the limited electroencephalographic data recorded in conventional clinical sleep studies, up to 256 channels of EEG data can be acquired and analyzed from a single polysomnographic session with our Net Station system (Electrical Geodesics, Inc., Eugene, OR). Net Station is a complete hardware and software system for working in the most sophisticated manner with EEG and event related potential (ERP) data. It is available for every recording bedroom in the facility.

Multiple Sleep Latency Testing

Multiple sleep latency testing (MSLT) is conducted according to a standard clinical protocol (“The Clinical Use of the MSLT and MWT” Sleep, 28(1)113 2005) and typically records the variables in the table below. The montage can be configured to meet the needs of individual research projects.

MSLT
Derivation Variable
LEOG EOG
REOG EOG
F3A2 EEG
F4A1 EEG
C3A2 EEG
C4A1 EEG
O1A2 EEG
O2A1 EEG
CHIN EEG
ECG I ECG
ECG II ECG

Maintenance of Wakefulness Testing

Maintenance of Wakefulness testing (MWT) is conducted and analyzed according to a standard clinical protocol (“The Clinical Use of the MSLT and MWT” Sleep, 28(1)113 2005) and typically records the variables in the table below. The montage and procedure can be configured to meet the needs of individual research projects.

MWT
Derivation Variable
LEOG EOG
REOG EOG
F3A2 EEG
F4A1 EEG
C3A2 EEG
C4A1 EEG
O1A2 EEG
O2A1 EEG
CHIN EEG
ECG I ECG
ECG II ECG

Ambulatory Monitoring

Portable monitoring devices can be set up for research subjects by laboratory staff, allowing assessment of cardio-respiratory variables out of the laboratory environment while the patient sleeps overnight at home. Wisconsin Sleep uses the Alice PDX Recorder (Respironics, Inc., Murrysville, PA) that can provide full, unattended polysomnography in a home setting. This monitors up to 21 channels for EEG, ECG, EOG, EMG, and respiratory (T-flow, P-flow, thoracic, oxymetry, pulse rate, and position.)

In addition, Wisconsin Sleep employs the Actiwatch system (Mini Mitter Company, Inc., Bend, OR) for actigraphic recording and analysis of circadian sleep-wake rhythms. The Actiwatch system can be employed to estimate sleep-wake patterns and light exposure over periods as long as one month from ambulatory subjects going about their daily routines. This procedure typically records the variables listed in the table below.

Actiwatch-L
Derivation Variable
Accelerometer Activity
Photodiode Illuminance

Other Services

Standard medical services, such as EKGs, blood draws, and physical exams are available upon request.